Research on the Association Between Transforming Growth Factor-beta 1 (TGF-β1) and Chronic Obstructive Pulmonary Disease (COPD)

Ying Zhu; Ninghui Mu

Research on the Association Between Transforming Growth Factor-beta 1 (TGF-β1) and Chronic Obstructive Pulmonary Disease (COPD)

Authors

Ying Zhu Department of General Practice, The First People’s Hospital of Yunnan Province, PR China, Affiliated Hospital of Kunming University of Science and Technology, The First People’s Hospital of Yunnan Province, PR China
Ninghui Mu Department of General Practice, The First People’s Hospital of Yunnan Province, PR China, Affiliated Hospital of Kunming University of Science and Technology, The First People’s Hospital of Yunnan Province, PR China

Keywords:

TGF-β1, COPD, extracellular matrix, fibrosis

Abstract

Transforming Growth Factor-beta 1 (TGF-β1) is a multifunctional cytokine involved in various cellular processes, including cell proliferation, differentiation, apoptosis, and the formation of the extracellular matrix. Chronic Obstructive Pulmonary Disease (COPD) is a common respiratory disease characterized by airflow limitation and lung tissue destruction. In recent years, increasing evidence has suggested that TGF-β1 plays a significant role in the pathogenesis of COPD. This paper reviews the latest research on the association between TGF-β1 and COPD, exploring the functions of TGF-β1 in COPD and its potential as a therapeutic target.

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Research on the Association Between Transforming Growth Factor-beta 1 (TGF-β1) and Chronic Obstructive Pulmonary Disease (COPD)

Published

2024-08-29

How to Cite

Zhu, Y., & Mu, N. (2024). Research on the Association Between Transforming Growth Factor-beta 1 (TGF-β1) and Chronic Obstructive Pulmonary Disease (COPD). Journal of Comprehensive Molecular Science and Genetics, 1(1). Retrieved from https://mbgm.journals.publicknowledgeproject.org/index.php/mbgm/article/view/3228