Research on the Association Between Mucin 5B (MUC5B) Gene and  Decline in Pulmonary Function in COPD

Ying Zhu; Ninghui Mu

Research on the Association Between Mucin 5B (MUC5B) Gene and Decline in Pulmonary Function in COPD

Authors

Ying Zhu Department of General Practice, The First People’s Hospital of Yunnan Province, PR China, Affiliated Hospital of Kunming University of Science and Technology, The First People’s Hospital of Yunnan Province, PR China
Ninghui Mu Department of General Practice, The First People’s Hospital of Yunnan Province, PR China, Affiliated Hospital of Kunming University of Science and Technology, The First People’s Hospital of Yunnan Province, PR China

Keywords:

MUC5B, Chronic Obstructive Pulmonary Disease, COPD, lung function decline, gene polymorphism

Abstract

Mucin 5B (MUC5B) is a major mucin secreted by airway epithelial cells, involved in the production and regulation of airway mucus. Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by airflow limitation and gradual decline in lung function. In recent years, polymorphisms in the MUC5B gene have been closely associated with the decline in lung function in COPD, suggesting that this gene may play a significant role in the pathogenesis of COPD. This paper reviews the research on the association between the MUC5B gene and the decline in lung function in COPD, exploring the expression of MUC5B and its impact on lung function in COPD patients.

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Research on the Association Between Mucin 5B (MUC5B) Gene and Decline in Pulmonary Function in COPD

Published

2024-08-29

How to Cite

Zhu, Y., & Mu, N. (2024). Research on the Association Between Mucin 5B (MUC5B) Gene and Decline in Pulmonary Function in COPD. Journal of Comprehensive Molecular Science and Genetics, 1(1). Retrieved from https://mbgm.journals.publicknowledgeproject.org/index.php/mbgm/article/view/3226